Two-family outbreak of botulism associated with the consumption of smoked ribs in Sichuan Province, China

SummaryBackgroundOn September 22, 2013, two patients from Sichuan Province, China presented with symptoms of food-borne botulism, a rare but fatal illness caused by the consumption of foods containing Clostridium botulinum neurotoxins.MethodsInvestigators reviewed the medical charts and food consumption histories, and interviewed patients and family members. Food samples and clinical specimens were tested for botulinum toxin and neurotoxin-producing Clostridium species by standard methods.ResultsThe first two index cases presented with cranial neuropathies and flaccid paralysis, and required mechanical ventilation. There were 12 confirmed outbreak-associated cases. Botulinum toxin type A was identified in the smoked ribs, and all of the patients had consumed the smoked ribs from the same local restaurant. The smoked ribs contained no added salt, sugar, or preservative. Botulinum toxin production likely resulted from the cold-smoking preparation method and inappropriate refrigeration.ConclusionsSmoked ribs produced by a local restaurant, contaminated with type A botulism, was the contributor to this outbreak. The supervision of food safety should be strengthened to prevent future outbreaks in China

Assessing the Influence of Land Use and Land Cover Datasets with Different Points in Time and Levels of Detail on Watershed Modeling in the North River Watershed, China

National Natural Science Foundation of China [40901100, 40810069004]Land use and land cover (LULC) information is an important component influencing watershed modeling with regards to hydrology and water quality in the river basin. In this study, the sensitivity of the Soil and Water Assessment Tool (SWAT) model to LULC datasets with three points in time and three levels of detail was assessed in a coastal subtropical watershed located in Southeast China. The results showed good agreement between observed and simulated values for both monthly and daily streamflow and monthly NH4+-N and TP loads. Three LULC datasets in 2002, 2007 and 2010 had relatively little influence on simulated monthly and daily streamflow, whereas they exhibited greater effects on simulated monthly NH4+-N and TP loads. When using the two LULC datasets in 2007 and 2010 compared with that in 2002, the relative differences in predicted monthly NH4+-N and TP loads were -11.0 to -7.8% and -4.8 to -9.0%, respectively. There were no significant differences in simulated monthly and daily streamflow when using the three LULC datasets with ten, five and three categories. When using LULC datasets from ten categories compared to five and three categories, the relative differences in predicted monthly NH4+-N and TP loads were -6.6 to -6.5% and -13.3 to -7.3%, respectively. Overall, the sensitivity of the SWAT model to LULC datasets with different points in time and levels of detail was lower in monthly and daily streamflow simulation than in monthly NH4+-N and TP loads prediction. This research provided helpful insights into the influence of LULC datasets on watershed modeling

Optimizing a Polynomial Function on a Quantum Simulator

Gradient descent method, as one of the major methods in numerical optimization, is the key ingredient in many machine learning algorithms. As one of the most fundamental way to solve the optimization problems, it promises the function value to move along the direction of steepest descent. For the vast resource consumption when dealing with high-dimensional problems, a quantum version of this iterative optimization algorithm has been proposed recently[arXiv:1612.01789]. Here, we develop this protocol and implement it on a quantum simulator with limited resource. Moreover, a prototypical experiment was shown with a 4-qubit Nuclear Magnetic Resonance quantum processor, demonstrating a optimization process of polynomial function iteratively. In each iteration, we achieved an average fidelity of 94\% compared with theoretical calculation via full-state tomography. In particular, the iterative point gradually converged to the local minimum. We apply our method to multidimensional scaling problem, further showing the potentially capability to yields an exponentially improvement compared with classical counterparts. With the onrushing tendency of quantum information, our work could provide a subroutine for the application of future practical quantum computers.Comment: 6+4 pages, 8 figure

Effects of Time-Varying Impulses on the Synchronization of Delayed Dynamical Networks

The effects of time-varying impulses on the synchronization of a class of general complex delayed dynamical networks are investigated. Different from the existing works, the impulses discussed here are time-varying, and both synchronizing and desynchronizing impulses are considered in the network model simultaneously. Moreover, the network topology is assumed to be directed and weakly connected with a spanning tree. By using the comparison principle, some simple yet generic globally exponential synchronization criteria are derived. It is shown that besides impulse strengths and impulsive interval, the obtained criteria are also closely related with topology structure of the network. Finally, numerical examples are given to demonstrate the effectiveness of the theoretical results

Measurement-device-independent quantum secure direct communication

Quantum secure direct communication (QSDC) is a unique technique, which supports the secure transmission of confidential information directly through a quantum channel without the need for a secret key and for ciphertext. Hence this secure communication protocol fundamentally differs from its conventional counterparts. In this article, we report the first measurement-device-independent (MDI) QSDC protocol relying on sequences of entangled photon pairs and single photons. Explicitly, it eliminates the security loopholes associated with the measurement device. Additionally, this MDI technique is capable of doubling the communication distance of its conventional counterpart operating without using our MDI technique. We also conceive a protocol associated with linear optical Bell-basis measurements, where only two of the four Bell-basis states could be measured. When the number of qubits in a sequence reduces to 1, the MDI-QSDC protocol degenerates to a deterministic MDI quantum key distribution protocol